1. Making "pre-energy" using the very energy needed is inefficient (but doable)
2. You want to prevent interconversion of purines (solved by negative feedback)
3. The intermediates in this pathway are known to be XXXXX
XXXXX XXXXX is definitely XXXXXXXX feedback, in XXXX XXXXXX states (XXXXXXXXX, XXXXXXXXX anemia, exercise, XXXXXXXXX), you XXXXXXXXXX XXX't XXXX XXXXX intermediates XX XXXXXXXX the XXXXXXXXX. We'll XXXXX XXXXX XX the XXXX XXXXXXXXXXX XX XXX XXX:XXX-dependentadenylosuccinate synthetase. Itmost likely XXXXXXXX toxic intermediates from accumulating. Of XXXXXX,again, we XXX't know XXX XXXX "why," but XXX XXXX that GTPis XXXX in XXX/XXXXXXXXXXXXX XXXXXXXXXXXXXXXXX the XXXXXX that the pathway's XXXXXX XXXXXXXXXXXX for production XXX always met.
To XXXX at it another way, let's XXX you XXX XXXXXXX out and you use up a XXX XX ATP.XXX XXXX to XXXXXXXXX XXXX XXXXXXXXX, XXX XXX XXXXXXX requires ATPto XXXX additional XXX (then XXX). See the XXXXXXX?Luckily, XXXX's XXX XXX XXXX here, XXXXX XXXXXX be used in lieu of XXX. Yes, XXX XXXXXXXXXXX XX XXXX XXX XXXXX functions, but this XXXXXXX XXXXX applies. You XXX think of an XXXXXXXXXX XXXXXX XXXXX lots XX XXXXXXXXXXXX eats XXX your - XXX - XXX, so you XXXX to replenish that.
XX for XXX XXX is needed for the other enzyme, it's simply the XXXX XXXXXXXX energy XXXXX in cells XXX XXX default one to use.
Speaking of which, thecommitted step XX XXXX shared XXXXXXX is the second step XXX XXXXXXXXXXXXXXXXXXX transferase (aka XXX ATP-dependent XXX). This XXXXX you have XX get GMPor XXX at the XXX, or else the XXXXXXXXXXXXX XXXX XXXXXXXXXX. XX you XXXX XXXXXXXXXXXX energy XX XXXXXXXX either XXXXXXX, XXXX XXX and XXXX XXXXX XXXXXXXX. XX XXXXXXX of XXXXXXXXXX past XXX committed step but not XXXXXXXXX is XXXXXXXX XXXXXXXXXXX (XX XXXXXXXXXXX).
XXXX, you are XXXXXXX: XXXXX are XXXX XXX regulatory XXXXXX: XXXX synthetase, XXXXXXXXXXXXXXXXXXX transferase, XXXXXXXXXXXXXXXX synthetase, and IMP XXXXXXXXXXXXX:
X. XXXXXX ADP (XXXXXXXXXXXXXXX)XXXXXXXXXXX XXXXXXXXXX
X. XXXXXX AMP XXXXXXX the XXXXXXXXXXXXXXXXXXX XXXXXXXXXXX
X. XXX XXXXXXXX XXX XXXXXXXXXXXXXXXX XXXXXXXXXX;GMPinhibits XXXXXXXXXXXXXXXX
XXX XXXX XXXXX XXXXXX XXXX XX left XX XXXXXXX XX XXXXXX XXXXXXX XXXXXXXX XX appreciate further the regulatory XXXXX of GTP/XXXXX purine XXXXXXXXXXXXXXX XXXXXXXXXX.