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During purine synthesis why does GTP activate ad
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<p>1. Making "pre-energy" using the very energy needed is inefficient (but doable)</p> <p>2. You want to prevent interconversion of purines (solved by negative feedback)</p> <p>3. The intermediates in this pathway XXX known to XX toxic</p> <p>XXXXX there XX XXXXXXXXXX XXXXXXXX XXXXXXXX, in <XXXXXX>XXXX XXXXXX XXXXXX</XXXXXX> (XXXXXXXXX, hemolytic anemia, XXXXXXXX, XXXXXXXXX), you definitely don't want <strong>toxic XXXXXXXXXXXXX</strong> XX compound the situation. XX'll XXXXX XXXXX XX the more XXXXXXXXXXX of XXX two:GTP-dependentadenylosuccinate synthetase. Itmost likely prevents toxic XXXXXXXXXXXXX from accumulating. XX course,again, we don't know XXX XXXX "why," but XXX fact XXXX XXXXX XXXX in XXX/XXXXXXXXXXXXX XXXXXXXXXXXXXXXXX the chance XXXX the pathway's XXXXXX requirements XXX production are XXXXXX met.</p> <p><strong>XX XXXX at it another XXX</strong>, let's say you XXX working out and you XXX XX a XXX XX XXX.XXX need to replenish your ATPstores, XXX the pathway requires XXXXX make additional XXX (XXXX ATP). See XXX XXXXXXX?Luckily, XXXX's not the XXXX here, XXXXX GTPcan be XXXX in lieu XX ATP. Yes, XXX XXXXXXXXXXX is used for XXXXX functions, but XXXX XXXXXXX still applies. XXX can XXXXX XX an XXXXXXXXXX XXXXXX where lots of XXXXXXXXXXXX eats XXX your - XXX - XXX, so you XXXX to XXXXXXXXX XXXX.</p> <p>As for why XXX XX needed XXX XXX other XXXXXX, it's XXXXXX the most abundant energy store in cells XXX the XXXXXXX XXX to XXX.</p> <p>Speaking of which, XXX<XXXXXX>XXXXXXXXX step of this shared pathway</strong><XXXXXX> XX the XXXXXX step via amidophosphoribosyl transferase</strong> (aka XXX ATP-dependent one). This XXXXX you XXXX XX XXX XXXXX XXX at XXX end, or XXXX XXX XXXXXXXXXXXXX will accumulate. XX you XXXX insufficient XXXXXX XX complete XXXXXX pathway, XXXX XXX and will cause XXXXXXXX. XX XXXXXXX of proceeding past XXX XXXXXXXXX step but not finishing is <XXXXXX>Fructose XXXXXXXXXXX (XX XXXXXXXXXXX)</strong>.</p> <p><strong>Last, you XXX XXXXXXX: there are four XXX regulatory points:</strong> XXXX XXXXXXXXXX, XXXXXXXXXXXXXXXXXXX XXXXXXXXXXX, adenylosuccinate synthetase, and IMP dehydrogenase:</p> <p>X. GDPand XXX (synergistically)inhibitPPRP synthetase</p> <p>2. GMPand XXX XXXXXXX the XXXXXXXXXXXXXXXXXXX XXXXXXXXXXX</p> <p>X. XXX XXXXXXXX XXX XXXXXXXXXXXXXXXX synthetase;XXXXXXXXXXX IMPdehydrogenase</p> <p>XXX XXXX XXXXX XXXXXX XXXX is left XX looking XX <XXXXXX>purine XXXXXXX XXXXXXXX</strong> to XXXXXXXXXX XXXXXXX XXX regulatory XXXXX XX GTP/XXXXX <XXXXXX>purine XXXXXXXXXXXXXXX XXXXXXXXXX</XXXXXX>.</p>">
